heart attack Tag's Archives
Mutant gene, responsible for the heart disease among, ten of millions of people from the subcontinent has
been isolated, according to a study.
The guilty gene, found in more than1.5 billion people only in South Asia, is definite to create heart trouble, usually in later life, the researchers said.
Scientists have already concluded that the India, Pakistan, Sri Lanka and to some extend Bangladesh, have a giant share in the global burden of cardiovascular diseases. According to the previous study, India alone will account for sixty percent of global heart issues, due to genetics and lifestyle, at the end of this year.
“The gene mutation induces the synthesis of an abnormal protein,” said the lead researcher. These include elevated high blood pressure and weakening of the heart muscles called cardiomyopathy, and finally death due to sudden heart attack.
In two side by side clinical trials, researchers perform the tests to check the mutation in 800 cardiac patients and 699 healthy persons across India.
The relation between the genetic defect and heart disease “were almost off the scale,” and confirming that the gene mutation played a key part in causing heart problems.
These findings raise a shocking question: if the mutation in the specific gene is so dangerous, what is the cause of its widespread?
alzheimer's, cardiovascular diseases, heart attack, high blood pressure, mutant gene
The U.S. FDA reaffirmed its stance that high level of LDL or “bad cholesterol,” is key risk factor for heart diseases such as heart attack, stroke etc, and reduction in LDL cholesterol lowers the risk of these diseases.
The agency was reviewing of data from ENHANCE, a trial, which was comparing Zocor (HMG-CoA reductase inhibitor), a drug inhibit the production of cholesterol in the liver, in combination to Vytorin with Zetia (ezemtimibe), which limits the cholesterol absorption.
Preliminary results from ENHANCE had shown that there was no considerable difference in the thickness of the walls of the blood vessels of the neck. Though, the LDL cholesterol reduction, in patients with Vytorin compared to Zocor was significant.
bad cholesterol, f.d.a, heart attack, heart diseases, stroke
