Previous researches have already mentioned that, people who donate kidney have no significant effect on the kidney function or survival, lead researcher Dr. Hassan N. Ibrahim said.
Researchers analyzed the data of 3,698 kidney donors from 1963 to 2007, to examine the long term safety. In 255 donors operated in 2003, researchers evaluated their GFR (glomerular filteration rate) also referred as 24 hours urinary creatinine clearance test, blood pressure and quality of life.
The normal range of GFR in healthy human is 90 to 120 mL/min and result values below 60, express renal dysfunction while value less than 15 express complete renal failure. Albumin in urine is another indication of kidney dysfunction.
There was no significant variation in the lab tests and survival between donors and non-donors, researchers reported. In addition, chronic diseases of kidney were more common in non-donors: 268 vs.180 cases per million per year.
Older age and greater body mass index (BMI) was linked to the high blood pressure and lesser GFR on enduring follow-up. On the contrary, long time after kidney donation didn’t link to GFR reduction and hypertension. Though, the slight decrease in albuminuria has been noticed.
Donors have no considerable change in their quality of life and even have better quality than the general population, researchers explained.
Still, findings of the current study “could encourage the expansion of the donor pool, but cautious optimism is warranted.” Dr. Hassan N. Ibrahim said.